3 Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea Health Functional Food Policy Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju, Republic of Korea.2 Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea BK21 FOUR Research Group for Omics-based Bio-health in Food Industry, Korea University, Sejong, Republic of Korea Biological Clock-based Anti-aging Convergence RLRC, Korea University, Sejong, Republic of Korea.1 Toxicological Evaluation and Research Department, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju, Republic of Korea Department of Food and Biotechnology, Korea University, Sejong, Republic of Korea.